Foliar fungicide applications have provided inconsistent yield increases in Ontario with an average yield response of 2.1 bu/ac (Figure 1). Only about 30% of the spray decisions produced a yield response that was economically beneficial to the producer. So far, no clear correlation to disease pressure, tillage practice, seed variety, or weather has been demonstrated for the level of yield response achieved with a fungicide. Recent work in corn has revealed that the yield response is highly dependent on the hybrid. This project was designed to assess whether soybean variety plays a significant role in the yield response to foliar fungicides. If some varieties respond more than others, this information could be important in making economic management decisions.